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Cisco and Nutanix have partnered to introduce the IT industry’s most complete hyperconverged solution by integrating and validating Cisco® servers, storage, networking, and SaaS operations with the Nutanix hybrid multicloud platform. Cisco Compute Hyperconverged with Nutanix is built, managed, and supported holistically to deliver a more seamless experience, foster innovation, and accelerate customers’ hybrid-cloud journeys. Modern workloads require modern flexibility. Traditional hyperconverged solutions require scaling compute and storage together. When you need to scale compute capacity without adding storage, Cisco Compute-Only (CO) nodes provide that critical capability—empowering you to design clusters that match your exact requirements.
The Cisco Compute X-Series System simplifies your data center, adapting to the unpredictable needs of modern applications while also providing for traditional scale-out and enterprise workloads. It reduces the number of server types to maintain, helping to improve operational efficiency and agility as it helps reduce complexity. Powered by the Cisco Intersight® cloud-operations platform, it shifts your focus from administrative details to business outcomes—with hybrid-cloud infrastructure that is assembled from the cloud, shaped to your workloads, and continuously optimized.
Cisco Compute-Only X210c M7 All NVMe Node
A). Expanding Cisco Compute Hyperconverged node cluster with Cisco Compute-Only node:
The Cisco Compute-Only node solution enables you to expand the compute resources of Cisco hyperconverged clusters running Nutanix by adding Cisco UCS®-certified servers without additional storage. These storage-less, Compute-Only (CO) servers certified by Cisco integrate seamlessly into your existing or new hyperconverged Nutanix cluster, allowing organizations to efficiently support compute-intensive applications by scaling processing resources independently of storage infrastructure.
Key benefits
● Cost-effective scaling for compute-heavy workloads
● Flexibility in cluster design
Table 1. Minimum cluster requirements for Cisco Compute-Only nodes
| Cluster attributes |
Hyperconverged node (HCI) with Cisco Compute-Only node |
| Number of nodes |
Minimum of 3 HCI nodes and minimum of 2 CO nodes |
| Nodes ratio |
Nutanix recommends the following nodes ratio: 1 HCI: 1 CO |
| Hypervisor |
Hyperconverged node: Nutanix AHV only Compute-Only node: Nutanix AHV only |
| Licensing |
NCI licenses on a per-core basis For more information about NCI licenses, see NCI section in Nutanix Cloud Platform Software Options |
| Nutanix Cloud Platform software |
Same as Cisco Compute Hyperconverged with Nutanix |
B). Cisco Compute-Only node connected to Pure Storage Flash Array (FlashStack with Nutanix)
Pure Storage FlashArray//X and FlashArray//XL delivers mission-critical performance with the efficiency and resiliency that’s missing from legacy arrays. FlashArray //X and FlashArray//XL packs more IOPS, ultra- consistent latency, and greater scale into a smaller footprint. Nondisruptive upgrades, always-on availability, and built-in data protection ensure workloads are always running while cutting risk. FlashArray//XL is designed to provide the highest performance density with a level of operational and management simplicity.
Nutanix Cloud Platform (NCP) consolidates computing, storage, and networking into a unified pool. It uses Nutanix Acropolis Operating System (AOS) for storage, Nutanix (Acropolis Hypervisor (AHV) for virtualization, and Prism Central for centralized management across environments.
The Cisco Compute-Only node with Nutanix Cloud Platform (NCP) and Pure Storage FlashArray solution delivers a disaggregated infrastructure architecture that enables independent scaling of compute and storage resources. This solution combines industry-standard Cisco Compute-Only node servers running Nutanix AHV and AOS connected to external Pure Storage FlashArray. This architecture leverages Pure software-defined storage environment optimized for enterprise workloads. The FlashStack solution with Nutanix integration provides organizations with the agility to adapt infrastructure resources dynamically while maintaining enterprise-level reliability and performance
Key benefits
● Independent scalability: scale compute and storage resources separately based on workload demands
● Enterprise-grade protection: built-in data protection and disaster recovery capabilities
● Hybrid-cloud readiness: seamlessly extend operations across on-premises and cloud environments
● Investment protection: use Nutanix Cloud Platform with existing external storage
| Attributes |
Cisco Compute-Only (CO) node connected to Pure Storage FlashArray |
| Cisco Compute-Only nodes |
Minimum total physical CPU core count per node: 24 |
| Minimum memory: 64 GB |
|
| M.2 boot drives with M.2 RAID controller (480GB is recommended.) |
|
| Storage protocol: NVMe over Fabric (NVMeoF) over TCP |
|
| 25Gb Ethernet network connection recommended between Cisco Nutanix Compute cluster and Pure Storage FlashArray (10Gb will be supported) |
|
| Minimum 5 CO nodes |
|
| Hypervisor |
Nutanix AHV only |
| Management |
Intersight Management Mode (IMM) |
| Pure Storage |
FlashArray//X and FlashArray//XL |
| Nutanix Cloud Platform software |
Supported Nutanix software:
● Nutanix Cloud Infrastructure (NCI)
● Nutanix Cloud Manager (NCM)
● Nutanix Cloud Platform (NCP)
● Nutanix Kubernetes Platform (NKP)
|
| Licensing |
Nutanix Cloud Infrastructure (NCI) licenses on a per-core basis Nutanix Cloud Infrastructure: compute (NCI-C) (2000 cores minimum) For more information about NCI licenses, see NCI section in Nutanix Cloud Platform Software Options |
The Cisco Compute-Only X210c M7 All NVMe Node provides these main features:
● CPU: up to 2x 5th Gen or 4th Gen Intel® Xeon® Scalable Processors with up to 64 cores per processor and up to 320 MB of Level-3 cache per CPU
● Memory: up to 8 TB of main memory with 32x 256 GB DDR5 5600 MT/s or DDR5 4800 MT/s DIMMs depending on the CPU installed
● Storage: up to six hot-pluggable Non-Volatile Memory express (NVMe) 2.5-inch drives with passthrough controllers, up to two M.2 SATA drives with hardware RAID. For Compute-Only (CO) node, these slots are not used.
● mLOM Virtual Interface Cards (VICs):
◦ Cisco UCS VIC 15420 occupies the server's modular LAN on motherboard (mLOM) slot, enabling up to 50 Gbps of unified fabric connectivity to each of the chassis’s intelligent fabric modules (IFMs) for 100 Gbps connectivity per server.
◦ Cisco UCS VIC 15231 occupies the server's modular LAN on motherboard (mLOM) slot, enabling up to 100 Gbps of unified fabric connectivity to each of the chassis’s intelligent fabric modules (IFMs) for 100 Gbps connectivity per server.
◦ Cisco UCS VIC 15230 occupies the server's modular LAN on motherboard (mLOM) slot, enabling up to 100 Gbps of unified fabric connectivity to each of the chassis’s intelligent fabric modules (IFMs) for 100 Gbps connectivity per server with secure boot technology.
● Optional mezzanine card:
◦ Cisco UCS 5th Gen virtual interface card (VIC) 15422 can occupy the server's mezzanine slot at the bottom rear of the chassis. This card's I/O connectors link to Cisco UCS X-Fabric technology. An included bridge card extends this VIC's 2x 50 Gbps of network connections through IFM connectors, bringing the total bandwidth to 100 Gbps per fabric (for a total of 200 Gbps per server) with secure-boot technology.
◦ Cisco UCS PCI Mezz card for X-Fabric can occupy the server's mezzanine slot at the bottom rear of the chassis. This card's I/O connectors link to Cisco UCS X-Fabric modules and enable connectivity to the Cisco UCS X440p PCIe Node.
◦ All VIC mezzanine cards also provide I/O connections from the X210c All NVMe node to the X440p PCIe Node.
● Security: The server supports an optional Trusted Platform Module (TPM). Additional features include a secure boot FPGA and ACT2 anti-counterfeit provisions.
The Cisco Compute-Only X210c M7 All NVMe Node incorporates 4th or 5th Gen Intel Xeon Scalable Processors with 60 percent more cores per socket and such advanced features as Intel Advanced Matrix Extensions (AMX), Data Streaming Accelerator (DSA), In-Memory Analytics Accelerator (IAA), and QuickAssist Technology (QAT), providing many applications with significant performance improvements.
The Cisco Compute-Only X210c M7 All NVMe Node can be repurposed as an HCI node by adding NVMe drives. For more information, please refer to Cisco Compute Hyperconverged with Nutanix-HCIX210c M7 All-NVMe Node specification document.
Software and management
Cisco Intersight simplifies infrastructure operations across on-premises data centers, edge sites, and public clouds. Intersight Managed Mode (IMM) is a newer architecture that manages the Cisco UCS fabric-interconnected systems through a Redfish-based standard model. In this mode, the X210c M7 All NVMe nodes are connected to a pair of Cisco UCS 6400 series, a pair of Cisco UCS 6500, or a pair of Cisco UCS 6600 fabric interconnects and managed by Intersight.
Nutanix Cloud Platform software: The Nutanix Cloud Platform (NCP) offering includes various software packages in multiple editions (Starter, Pro, and Ultimate) to meet customer’s infrastructure needs with the right set of capabilities.
● Nutanix Cloud Infrastructure (NCI) is a complete software stack to unify your hybrid-cloud infrastructure including compute, storage and network, hypervisors, and containers, in public or enterprise clouds.
● Nutanix Cloud Manager (NCM) software allows enterprises to build, use, operate, and govern their applications and IT infrastructure by offering intelligent operations, including monitoring, insights, and automated remediation. Self-service and orchestration capabilities help to streamline team tasks for scaling applications in a hybrid-cloud environment.
Hypervisor: The Cisco Compute-Only X210c M7 All NVMe Node supports Nutanix Acropolis Hypervisor (AHV) only.
Management mode: The Cisco Compute-Only X210c M7 All NVMe Node supports only Intersight Management Mode (IMM).
Since we first delivered the Cisco Unified Computing System™ (Cisco UCS) in 2009, our goal has been to simplify the data center. We pulled management out of servers and into the network. We simplified multiple networks into a single unified fabric. And we eliminated network layers in favor of a flat topology wrapped into a single unified system. With the Cisco Compute Hyperconverged X-Series System, we take that simplicity to the next level:
● Simplified operations with a solution that combines the operational simplicity of hyperconverged software with the efficiency and flexibility of a modular system
● Increased agility and response to the dynamic needs of your business with a solution that is inherently easy to scale and includes support for future generations of processors, storage, accelerators, networking technologies, and SaaS innovations
● Improved sustainability with a solution that is engineered to be more energy efficient and can be easily upgraded and reused, lowering the consumption of power and raw materials when compared to traditional rack servers
Table 2. Product specifications
| Item |
Specifications |
| Processors |
Either: Up to 2x 5thGen Intel Xeon Scalable Processors (1 or 2) Or: Up to 2x 4thGen Intel Xeon Scalable Processors (1 or 2) |
| Memory |
Either: 32 DDR5-5600 DIMM slots (16 DIMMS per CPU): 16, 32, 48, 64, 96, 128, 256 GB at up to 5,600 MT/s for up to 8 TBof memory with 5th Gen Intel Xeon Scalable Processors Or: 32 DDR5-4800 DIMM slots (16 DIMMS per CPU): 16, 32, 64, 128, 256 GB at up to 4,800 MT/s for up to 8 TBof memory with 4th Gen Intel Xeon Scalable Processors |
| mLOM |
mLOM slot for VIC 15420, VIC 15231, or VIC 15230 |
| Mezzanine adapter (rear) |
15422 mezzanine card with VIC 15000 bridge connector compatible with VIC 15420 |
| Mezzanine module (front) |
Front mezzanine module options:
● Cisco FlexStorage NVMe passthrough controller (for NVMe drives only)
● No front mezzanine
|
| Boot drive options |
● Mini-storage module with 2x M.2 (up to 480GB per drive) SATA drives with hardware RAID for hypervisor boot
|
| GPUs |
● NVIDIA H100 Tensor Core GPU (dual slot)
● NVIDIA L40S GPU (dual slot)
● NVIDIA L4 Tensor Core GPU (single slot)
● NVIDIA A16 GPU (dual slot)
GPU support requires Cisco Compute Hyperconverged X-Series Gen4 PCIe Node (HCIX-440P-U) |
| Riser options |
● Riser A for 1x dual-slot GPU per riser
● Riser B for 2x single-slot GPUs per riser
|
| Management |
|
| Temperature: operating |
50° to 95°F (10° to 35°C) |
| Temperature: nonoperating |
-40° to 149°F (–40° to 65°C) |
| Humidity: operating |
5% to 90% noncondensing |
| Humidity: nonoperating |
5% to 90% noncondensing |
| Altitude: operating |
0 to 10,000 ft (0 to 3000m); maximum ambient temperature decreases by 1°C per 300m |
| Altitude: nonoperating |
40,000 ft (12,000m) |
Table 3. System requirements
| Item |
Requirements |
| Cisco UCS X-Series chassis |
Cisco Compute Hyperconverged X9508 Chassis |
| Fabric interconnect |
6454, 64108, 6536 and 6600 fabric interconnects |
| Cisco UCS X-Fabric modules |
9416 X-Fabric Modules for Cisco Compute Hyperconverged X9508 Chassis |
| Cisco Intersight |
Intersight Managed Mode (minimum Essentials license per server) |
Table 4 provides ordering information for the Cisco Compute-only X210c M7 All NVMe Node.
| Part number |
Description |
| HCIX-M7-MLB |
Cisco Compute Hyperconverged and Compute-Only Node X-Series M7 with Nutanix MLB |
| HCOX210C-M7SN |
Cisco Compute-Only X210c M7 Node w/o CPU, memory, storage, mezzanine |
| HCOX210C-M7SN-U |
Cisco Compute-Only X210c M7 Node UPG w/o CPU, memory, storage, mezzanine |
For information about installing or upgrading your server, see the Hardware Installation Guide.
For ordering information, see the Cisco Compute Compute-Only X210c M7 All NVMe Node spec sheet.
The Cisco Compute-Only X210c M7 All NVMe Node has a three-year next-business-day (NBD) hardware warranty and a 90-day software warranty.
Augmenting the Cisco Unified Computing System warranty, Cisco Smart Net Total Care® and Cisco Solution Support services are part of Cisco’s technical services portfolio. Cisco Smart Net Total Care combines Cisco’s industry-leading and award-winning foundational technical services with an extra level of actionable business intelligence that is delivered to you through the smart capabilities in the Cisco Smart Net Total Care portal.
For more information, please refer to https://www.cisco.com/c/en/us/support/services/smart-net-total-care/index.html.
Cisco Solution Support includes both Cisco product and solution-level support, resolving complex issues in multivendor environments on average 43 percent more quickly than with product support alone. Cisco Solution Support is a critical element in data-center administration, helping rapidly resolve issues encountered while maintaining performance, reliability, and return on investment.
This service centralizes support across your multivendor Cisco environment for both our products and solution partner products that you have deployed in your ecosystem. Whether there is an issue with a Cisco product or with a solution partner product, just call us. Our experts are the primary point of contact and own the case from first call to resolution.
For more information, please refer to https://www.cisco.com/c/en/us/services/technical/solution-support.html.
Information about Cisco’s environmental, social, and governance (ESG) initiatives and performance is provided in Cisco’s corporate social responsibility (CSR) and sustainability reporting.
Table 5. Cisco environmental sustainability information
| Sustainability topic |
Reference |
|
| General |
Information on product-material-content laws and regulations |
|
| Information on electronic waste laws and regulations, including our products, batteries, and packaging |
||
| Information on product takeback and reuse program |
||
| Sustainability inquiries |
Contact: csr_inquiries@cisco.com |
|
| Material |
Product packaging weight and materials |
Contact: environment@cisco.com |
Product environmental information
Product environmental information for users per Commission Regulation (EU) 2019/424 https://www.cisco.com/web/dofc/23906228.pdf.
Cisco and our industry-leading partners deliver services that accelerate your transition to a Cisco UCS X-Series Compute-Only node system solution. Cisco Unified Computing Services can help you create an agile infrastructure, accelerate time to value, reduce costs and risks, and maintain availability during deployment and migration. After deployment, our services can help you improve performance, availability, and resiliency as your business needs evolve and help you further mitigate risk.
For more information, visit https://www.cisco.com/go/unifiedcomputingservices.
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| New or revised topic |
Described in |
Date |
| Cisco Compute-Only X210c M7 All NVMe Node |
Data sheet |
December 2025 |