About Adaptive Profiles
With adaptive profiles you can:
Enable access control rules to perform application and file control, includig AMP, and intrusion rules to use service metadata.
Adaptive profiling must be enabled (its default state) as described in Configuring Adaptive Profiles for access control rules to perform application and file control, including AMP, and for intrusion rules to use service metadata.
For passive deployments, enable adaptive profile updates to defragment and reassemble IP traffic according to the destination hosts' operating systems.
For inline deployments Cisco recommends that, instead of enabling adaptive profile updates, you configure the inline normalization preprocessor with the Normalize TCP Payload option enabled.