Required IPs and Ports for Secure Malware Analytics

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Updated:October 17, 2024
Document ID:214465

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Introduction

This document outlines the essential network configurations you need to implement on your firewall to ensure seamless operation of Secure Malware Analytics.

Secure Malware Analytics Clouds

US (United States) Cloud

Access URL: https://panacea.threatgrid.com

Hostname IP Port Details

panacea.threatgrid.com

IPv4:

63.97.201.67

63.162.55.67

IPv6:

2602:811:9007:6::61

2602:811:900b:6::6e

443

For Secure Malware Analytics Portal and Integrated Devices (ESA/WSA/FTD/ODNS/Meraki)

glovebox.chi.threatgrid.com

IPv4: 200.194.241.35

IPv6:

2602:811:900f:6::6e

443

Sample Interaction window

glovebox.rcn.threatgrid.com

IPv4:

63.97.201.67

IPv6:

2602:811:9007:6::61

443

Sample Interaction window

glovebox.scl.threatgrid.com

IPv4:

63.162.55.67

IPv6:

2602:811:900b:6::6e

443

Sample Interaction window

fmc.api.threatgrid.com

IPv4:

63.97.201.67

63.162.55.67

IPv6:

2602:811:9007:6::61

2602:811:900b:6::6e

443

FMC/FTD File Analysis Service

EU (Europe) Cloud

Access URL: https://panacea.threatgrid.eu

Hostname IP Port Details

panacea.threatgrid.eu

IPv4:

62.67.214.195

200.194.242.35

200.194.245.35

IPv6:

2602:811:9006:6::6e

2602:811:900c:6::6e

443

For Secure Malware Analytics Portal and Integrated Devices (ESA/WSA/FTD/ODNS/Meraki)

glovebox.muc.threatgrid.eu

IPv4:

62.67.214.195

200.194.245.35

IPv6:

2602:811:900c:6::6e

3

Sample Interaction window

glovebox.fam.threatgrid.eu

IPv4:

200.194.242.35

IPv6:

2602:811:9006:6::6e

443

Sample Interaction window

fmc.api.threatgrid.eu

IPv4:

62.67.214.195

200.194.242.35

200.194.245.35

IPv6:

2602:811:9006:6::6e

2602:811:900c:6::6e

443

FMC/FTDFile Analysis Service

The old IP 89.167.128.132 has been retired, please update your firewall rules with above IPs.

CA (Canada) Cloud

Access URL: https://panacea.threatgrid.ca

Hostname IP Port Details

panacea.threatgrid.ca

IPv4:

200.194.240.35

IPv6:

2602:811:900d:6::6e

443

For Secure Malware Analytics Portal and Integrated Devices (ESA/WSA/FTD/ODNS/Meraki)

glovebox.kam.threatgrid.ca

IPv4:

200.194.240.35

IPv6:

2602:811:900d:6::6e

443

Sample Interaction window
fmc.api.threatgrid.ca

IPv4:

200.194.240.35

IPv6:

2602:811:900d:6::6e

443

FMC/FTD File Analysis Service

AU (Australia) Cloud

Access URL: https://panacea.threatgrid.com.au

Hostname IP Port Details

panacea.threatgrid.com.au

IPv4:

200.194.246.35

200.194.247.35

IPv6:

2602:811:900e:6::6e

2602:811:9003:6::6e

443

For Secure Malware Analytics Portal and Integrated Devices (ESA/WSA/FTD/ODNS/Meraki)

glovebox.syd.threatgrid.com.au

IPv4:

200.194.246.35

200.194.247.35

IPv6:

2602:811:900e:6::6e

2602:811:9003:6::6e

443

Sample Interaction window
fmc.api.threatgrid.com.au

IPv4:

200.194.246.35

200.194.247.35

IPv6:

2602:811:900e:6::6e

2602:811:9003:6::6e

443

FMC/FTD File Analysis Service

IN (India) Cloud

Access URL: https://panacea.threatgrid.in

Hostname IP Port Details

panacea.threatgrid.in

IPv4:

200.194.244.35

IPv6:

2602:811:9001:6::6e

443

For Secure Malware Analytics Portal and Integrated Devices (ESA/WSA/FTD/ODNS/Meraki)

glovebox.bom.threatgrid.in

IPv4:

200.194.244.35

IPv6:

2602:811:9001:6::6e

443

Sample Interaction window
fmc.api.threatgrid.com.in

IPv4:

200.194.244.35

IPv6:

2602:811:9001:6::6e

443

FMC/FTD File Analysis Service

Secure Malware Analytics Appliance

The following are the recommended firewall rules per interface of the Secure Malware Analytics Appliance.

Dirty Interface

This is used by VMs to communicate with the internet so that samples can resolve DNS and communicate with command and control (C&C) servers. Allow:

Direction Protocol Port Destination Hostname Details

Outbound

IP

ANY

ANY

Recommended except where specified in the Deny section here.

Used to allow connectivity for analysis.

Outbound

TCP

22

63.97.201.98

63.162.55.98

support-snapshots.threatgrid.com

Used for automatic support diagnostic uploads. Note: Requires software version 1.2+.

Outbound

TCP

22

63.162.55.97

63.97.201.97

appliance-updates.threatgrid.com

Appliance Updates

Outbound

TCP

19791

63.97.201.96

63.162.55.96

rash.threatgrid.com

Remote Support / Appliance Support Mode

Outbound

TCP

22

63.97.201.99

63.162.55.99

appliance-licensing.threatgrid.com

License Management

Remote Network Exit

This is used by the appliance to tunnel VM traffic to a remote exit formerly known as tg-tunnel.

Direction Protocol Port Destination

Outbound

TCP

21413

173.198.252.53

Outbound

TCP

21417

69.55.5.250

Outbound

TCP

21415

69.55.5.250

Outbound

TCP

21413

38.123.149.87

Note: As of July 25, 2026, the following Remote Exit IP addresses have been replaced:
- 163.182.175.193 was replaced by 173.198.252.53
- 76.8.60.91 was replaced by 38.123.149.87

Deny:

Direction Protocol Port(s) Destination Details

Outbound

SMTP

ANY

ANY

To prevent malware from sending out spam.

Inbound

IP

ANY

Secure Malware Analytics Appliance Dirty Interface

Recommended except where specified in the Allow section above.

Used to allow communication for analysis.

Clean Interface

This is used by various connected services to submit samples as well as UI access for analysts. Allow:

Direction Protocol Port(s) Destination Details

Inbound

TCP

443 and 8443

Secure Malware Analytics Appliance Clean Interface

WebUI and API access

Inbound

TCP

9443

Secure Malware Analytics Appliance Clean Interface

Used for Glovebox

Inbound

TCP

22

Secure Malware Analytics Appliance Clean Interface

Admin TUI access over SSH

Outbound

TCP

19791

Host: rash.threatgrid.com

63.97.201.96

63.162.55.96

Recovery Mode for Secure Malware Analytics Support

Admin Interface

Use this to access the administration console or user interface. Allow:

Direction Protocol Port(s) Destination Details

Inbound

TCP

443 and 8443

Secure Malware Analytics Appliance Admin Interface

Used to configure settings for hardware and licensing

Inbound

TCP

22

Secure Malware Analytics Appliance Admin Interface

Admin TUI access over SSH

Revision History

Revision Publish Date Comments
9.0
17-Oct-2024
Addition of IPv6 addresses
8.0
12-Jul-2024
Added the IP Requirements for the new Australia Cloud, Updated the Network Requirements for the EU Region, Added New Glovebox IP in NAM
3.0
23-Oct-2023
Updated the Required IP Information
2.0
03-Oct-2023
Updated the Network Requirements for Canada DC
1.0
06-Oct-2021
Initial Release
TAC Authored

Contributed by Cisco Engineers

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